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An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis

The evolutionary conserved NSL complex is a prominent epigenetic regulator controlling expression of thousands of genes. Here we uncover a novel function of the NSL complex members in mitosis. As the cell enters mitosis, KANSL1 and KANSL3 undergo a marked relocalisation from the chromatin to the mit...

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Detalles Bibliográficos
Autores principales: Meunier, Sylvain, Shvedunova, Maria, Van Nguyen, Nhuong, Avila, Leonor, Vernos, Isabelle, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918316/
https://www.ncbi.nlm.nih.gov/pubmed/26243146
http://dx.doi.org/10.1038/ncomms8889