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An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis
The evolutionary conserved NSL complex is a prominent epigenetic regulator controlling expression of thousands of genes. Here we uncover a novel function of the NSL complex members in mitosis. As the cell enters mitosis, KANSL1 and KANSL3 undergo a marked relocalisation from the chromatin to the mit...
Autores principales: | Meunier, Sylvain, Shvedunova, Maria, Van Nguyen, Nhuong, Avila, Leonor, Vernos, Isabelle, Akhtar, Asifa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918316/ https://www.ncbi.nlm.nih.gov/pubmed/26243146 http://dx.doi.org/10.1038/ncomms8889 |
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