Cargando…

The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores

Accumulation of PLK1 at kinetochores is essential for chromosome alignment and segregation; however, the mechanism underlying PLK1 recruitment to kinetochores remains unresolved. The chromatin remodeller RSF1 tightly associates with centromere proteins, but its mitotic function is unknown. Here we s...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Ho-Soo, Park, Yong-Yea, Cho, Mi-Young, Chae, Sunyoung, Yoo, Young-Suk, Kwon, Myung-Hee, Lee, Chang-Woo, Cho, Hyeseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918322/
https://www.ncbi.nlm.nih.gov/pubmed/26259146
http://dx.doi.org/10.1038/ncomms8904