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IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis

Macrophage dysfunction plays a pivotal role during neovascular proliferation in diseases of ageing including cancers, atherosclerosis and blinding eye disease. In the eye, choroidal neovascularization (CNV) causes blindness in patients with age-related macular degeneration (AMD). Here we report that...

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Detalles Bibliográficos
Autores principales:	Nakamura, Rei, Sene, Abdoulaye, Santeford, Andrea, Gdoura, Abdelaziz, Kubota, Shunsuke, Zapata, Nicole, Apte, Rajendra S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330/ https://www.ncbi.nlm.nih.gov/pubmed/26260587 http://dx.doi.org/10.1038/ncomms8847

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