Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription

For therapeutic applications of siRNA, there are technical challenges with respect to targeted and systemic delivery. We here report a new siRNA carrier, RNAtr NPs, in a way that multiple tandem copies of RNA hairpins as a result of rolling circle transcription (RCT) can be readily adapted in tumour...

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Detalles Bibliográficos
Autores principales: Jang, Mihue, Kim, Jong Hwan, Nam, Hae Yun, Kwon, Ick Chan, Ahn, Hyung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918333/
https://www.ncbi.nlm.nih.gov/pubmed/26246279
http://dx.doi.org/10.1038/ncomms8930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918333/
https://www.ncbi.nlm.nih.gov/pubmed/26246279
http://dx.doi.org/10.1038/ncomms8930

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