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MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation

Myocyte enhancer factor 2B (MEF2B) is a transcription factor with mutation hotspots at K4, Y69 and D83 in diffuse large B-cell lymphoma (DLBCL). To provide insight into the regulatory network of MEF2B, in this study, we analyse global gene expression and DNA-binding patterns. We find that candidate...

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Detalles Bibliográficos
Autores principales:	Pon, Julia R., Wong, Jackson, Saberi, Saeed, Alder, Olivia, Moksa, Michelle, Grace Cheng, S. -W., Morin, Gregg B., Hoodless, Pamela A., Hirst, Martin, Marra, Marco A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918335/ https://www.ncbi.nlm.nih.gov/pubmed/26245647 http://dx.doi.org/10.1038/ncomms8953

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