Critical analysis of an oncolytic herpesvirus encoding granulocyte-macrophage colony stimulating factor for the treatment of malignant melanoma

Oncolytic viruses that selectively lyse tumor cells with minimal damage to normal cells are a new area of therapeutic development in oncology. An attenuated herpesvirus encoding the granulocyte-macrophage colony stimulating factor (GM-CSF), known as talimogene laherparepvec (T-VEC), has been identif...

Descripción completa

Detalles Bibliográficos
Autores principales: Hughes, Tasha, Coffin, Robert S, Lilley, Caroline E, Ponce, Rafael, Kaufman, Howard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918360/
https://www.ncbi.nlm.nih.gov/pubmed/27512660
http://dx.doi.org/10.2147/OV.S36701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918360/
https://www.ncbi.nlm.nih.gov/pubmed/27512660
http://dx.doi.org/10.2147/OV.S36701

Ejemplares similares