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Reovirus in cancer therapy: an evidence-based review

Reovirus, a double-stranded ribonucleic acid virus and benign human pathogen, preferentially infects and kills cancer cells in its unmodified form, and is one of the leading oncolytic viruses currently undergoing clinical trials internationally. With 32 clinical trials completed or ongoing thus far,...

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Detalles Bibliográficos
Autores principales: Clements, Derek, Helson, Erin, Gujar, Shashi A, Lee, Patrick WK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918368/
https://www.ncbi.nlm.nih.gov/pubmed/27512664
http://dx.doi.org/10.2147/OV.S51321