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Combining HDAC inhibitors with oncolytic virotherapy for cancer therapy
Histone deacetylase (HDAC) enzymes play a critical role in the epigenetic regulation of cellular functions and signaling pathways in many cancers. HDAC inhibitors (HDACi) have been validated for single use or in combination with other drugs in oncologic therapeutics. An even more novel combination t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918398/ https://www.ncbi.nlm.nih.gov/pubmed/27512681 http://dx.doi.org/10.2147/OV.S66081 |