Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases

Lactate and malate dehydrogenases (LDH and MDH) are homologous, core metabolic enzymes common to nearly all living organisms. LDHs have evolved convergently from MDHs at least four times, achieving altered substrate specificity by a different mechanism each time. For instance, the LDH of anaerobic t...

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Detalles Bibliográficos
Autores principales: Steindel, Phillip A., Chen, Emily H., Wirth, Jacob D., Theobald, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918429/
https://www.ncbi.nlm.nih.gov/pubmed/26889885
http://dx.doi.org/10.1002/pro.2904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918429/
https://www.ncbi.nlm.nih.gov/pubmed/26889885
http://dx.doi.org/10.1002/pro.2904

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