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Suppression of calcium-sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy
The calcium-sensing receptor (CaSR) releases intracellular calcium ([Ca(2+)](i)) by accumulating inositol phosphate. Changes in [Ca(2+)](i) initiate myocardial hypertrophy. Furthermore, autophagy associated with [Ca(2+)](i). Autophagy has previously been demonstrated to participate in the hypertroph...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918534/ https://www.ncbi.nlm.nih.gov/pubmed/27176663 http://dx.doi.org/10.3892/mmr.2016.5279 |