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Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse
Mechanical loading on pelvic supports contributes to pelvic organ prolapse (POP). However, the underlying mechanisms remain to be elucidated. Our previous study identified that mechanical strain induced oxidative stress (OS) and promoted apoptosis and senescence in pelvic support fibroblasts. The ai...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918563/ https://www.ncbi.nlm.nih.gov/pubmed/27176043 http://dx.doi.org/10.3892/mmr.2016.5264 |