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Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse

Mechanical loading on pelvic supports contributes to pelvic organ prolapse (POP). However, the underlying mechanisms remain to be elucidated. Our previous study identified that mechanical strain induced oxidative stress (OS) and promoted apoptosis and senescence in pelvic support fibroblasts. The ai...

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Detalles Bibliográficos
Autores principales:	LI, BING-SHU, GUO, WEN-JUN, HONG, LI, LIU, YAO-DAN, LIU, CHENG, HONG, SHA-SHA, WU, DE-BIN, MIN, JIE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918563/ https://www.ncbi.nlm.nih.gov/pubmed/27176043 http://dx.doi.org/10.3892/mmr.2016.5264

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