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Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction

Background. The relevance of antibodies (Abs) in the defense against Mycobacterium tuberculosis infection remains uncertain. We investigated the role of Abs to the mycobacterial capsular polysaccharide arabinomannan (AM) and its oligosaccharide (OS) fragments in humans. Methods. Sera obtained from 2...

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Detalles Bibliográficos
Autores principales: Chen, Tingting, Blanc, Caroline, Eder, Anke Z., Prados-Rosales, Rafael, Souza, Ana Camila Oliveira, Kim, Ryung S., Glatman-Freedman, Aharona, Joe, Maju, Bai, Yu, Lowary, Todd L., Tanner, Rachel, Brennan, Michael J., Fletcher, Helen A., McShane, Helen, Casadevall, Arturo, Achkar, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918826/
https://www.ncbi.nlm.nih.gov/pubmed/27056953
http://dx.doi.org/10.1093/infdis/jiw141