Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza

The development of next-generation influenza vaccines that elicit strain-transcendent immunity against both seasonal and pandemic viruses is a key public health goal. Targeting the evolutionarily conserved epitopes on the stem of influenza’s major surface molecule, hemagglutinin, is an appealing pro...

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Detalles Bibliográficos
Autores principales: Zarnitsyna, Veronika I., Lavine, Jennie, Ellebedy, Ali, Ahmed, Rafi, Antia, Rustom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918916/
https://www.ncbi.nlm.nih.gov/pubmed/27336297
http://dx.doi.org/10.1371/journal.ppat.1005692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918916/
https://www.ncbi.nlm.nih.gov/pubmed/27336297
http://dx.doi.org/10.1371/journal.ppat.1005692

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