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Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells

Stromal cells are generally considered to be derived primarily from the host's normal mesenchymal stromal cells or bone marrow. However, the origins of stromal cells have been quite controversial. To determine the role of polyploidy in tumor development, we examined the fate of normal mullerian...

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Detalles Bibliográficos
Autores principales: Zhang, Shiwu, Mercado-Uribe, Imelda, Sood, Anil, Bast, Robert C., Liu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918945/
https://www.ncbi.nlm.nih.gov/pubmed/27382431
http://dx.doi.org/10.18632/genesandcancer.102