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Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells
Stromal cells are generally considered to be derived primarily from the host's normal mesenchymal stromal cells or bone marrow. However, the origins of stromal cells have been quite controversial. To determine the role of polyploidy in tumor development, we examined the fate of normal mullerian...
Autores principales: | Zhang, Shiwu, Mercado-Uribe, Imelda, Sood, Anil, Bast, Robert C., Liu, Jinsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918945/ https://www.ncbi.nlm.nih.gov/pubmed/27382431 http://dx.doi.org/10.18632/genesandcancer.102 |
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