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Epigenetically silenced GNG4 inhibits SDF1α/CXCR4 signaling in mesenchymal glioblastoma

The most common and aggressive form of primary brain tumor in adults is glioblastoma (GBM). From the global DNA methylation profiling study, previously published from our laboratory, we identified Guanine Nucleotide binding-protein Gamma subunit 4 (GNG4) to be one of the most hyper methylated and do...

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Detalles Bibliográficos
Autores principales: Pal, Jagriti, Patil, Vikas, Mondal, Baisakhi, Shukla, Sudhanshu, Hegde, Alangar S., Arivazhagan, Arimappamagan, Santosh, Vani, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918951/
https://www.ncbi.nlm.nih.gov/pubmed/27382437
http://dx.doi.org/10.18632/genesandcancer.105