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Hypoxic Stress Induced by Hydralazine Leads to a Loss of Blood-Brain Barrier Integrity and an Increase in Efflux Transporter Activity

Understanding cellular and molecular mechanisms induced by hypoxic stress is crucial to reduce blood-brain barrier (BBB) disruption in some neurological diseases. Since the brain is a complex organ, it makes the interpretation of in vivo data difficult, so BBB studies are often investigated using in...

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Detalles Bibliográficos
Autores principales: Chatard, Morgane, Puech, Clémentine, Roche, Frederic, Perek, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919080/
https://www.ncbi.nlm.nih.gov/pubmed/27337093
http://dx.doi.org/10.1371/journal.pone.0158010