Decreased renal AT(1) receptor binding in rats after subtotal nephrectomy: PET study with [(18)F]FPyKYNE-losartan

BACKGROUND: Significant renal mass reduction induced by 5/6 subtotal nephrectomy (Nx) is associated with a chain of events that culminates in hypertension and chronic kidney disease (CKD). Numerous studies have provided evidence for the role of angiotensin (Ang) II type 1 receptor (AT(1)R) in the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ismail, Basma, deKemp, Robert A., Hadizad, Tayebeh, Mackasey, Kumiko, Beanlands, Rob S., DaSilva, Jean N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919198/
https://www.ncbi.nlm.nih.gov/pubmed/27339045
http://dx.doi.org/10.1186/s13550-016-0209-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919198/
https://www.ncbi.nlm.nih.gov/pubmed/27339045
http://dx.doi.org/10.1186/s13550-016-0209-4

Ejemplares similares