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Decreased renal AT(1) receptor binding in rats after subtotal nephrectomy: PET study with [(18)F]FPyKYNE-losartan
BACKGROUND: Significant renal mass reduction induced by 5/6 subtotal nephrectomy (Nx) is associated with a chain of events that culminates in hypertension and chronic kidney disease (CKD). Numerous studies have provided evidence for the role of angiotensin (Ang) II type 1 receptor (AT(1)R) in the pr...
Autores principales: | Ismail, Basma, deKemp, Robert A., Hadizad, Tayebeh, Mackasey, Kumiko, Beanlands, Rob S., DaSilva, Jean N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919198/ https://www.ncbi.nlm.nih.gov/pubmed/27339045 http://dx.doi.org/10.1186/s13550-016-0209-4 |
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