Renal PET-imaging with (11)C-metformin in a transgenic mouse model for chronic kidney disease

BACKGROUND: Organic cation transporters (OCTs) in the renal proximal tubule are important for the excretion of both exo- and endogenous compounds, and chronic kidney disease (CKD) alter the expression of OCT. Metformin is a well-known substrate for OCT, and recently, we demonstrated that positron em...

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Detalles Bibliográficos
Autores principales: Pedersen, Lea, Jensen, Jonas Brorson, Wogensen, Lise, Munk, Ole Lajord, Jessen, Niels, Frøkiær, Jørgen, Jakobsen, Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919269/
https://www.ncbi.nlm.nih.gov/pubmed/27339044
http://dx.doi.org/10.1186/s13550-016-0211-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919269/
https://www.ncbi.nlm.nih.gov/pubmed/27339044
http://dx.doi.org/10.1186/s13550-016-0211-x

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