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Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds
Modern strategies in drug development employ in silico techniques in the design of compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity parameters. The quality of the results depends on software algorithm, data library and input data. Compared to simulations of absorpt...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919356/ https://www.ncbi.nlm.nih.gov/pubmed/27445817 http://dx.doi.org/10.3389/fphar.2016.00181 |