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Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds

Modern strategies in drug development employ in silico techniques in the design of compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity parameters. The quality of the results depends on software algorithm, data library and input data. Compared to simulations of absorpt...

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Detalles Bibliográficos
Autores principales: Fröhlich, Eleonore, Mercuri, Annalisa, Wu, Shengqian, Salar-Behzadi, Sharareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919356/
https://www.ncbi.nlm.nih.gov/pubmed/27445817
http://dx.doi.org/10.3389/fphar.2016.00181