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Higher Brain Perfusion May Not Support Memory Functions in Cognitively Normal Carriers of the ApoE ε4 Allele Compared to Non-Carriers

Age-related changes in cerebral blood flow (CBF), which carries necessary nutrients to the brain, are associated with increased risk for mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Whether the association between CBF and cognition is moderated by apolipoprotein E (ApoE) ε4 genotype...

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Detalles Bibliográficos
Autores principales: Zlatar, Zvinka Z., Bischoff-Grethe, Amanda, Hays, Chelsea C., Liu, Thomas T., Meloy, M. J., Rissman, Robert A., Bondi, Mark W., Wierenga, Christina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919360/
https://www.ncbi.nlm.nih.gov/pubmed/27445794
http://dx.doi.org/10.3389/fnagi.2016.00151