Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

Argonaute proteins are key players in the gene silencing mechanisms mediated by small nucleic acids in all domains of life from bacteria to eukaryotes. However, little is known about the Argonaute protein that recognizes guide RNA/target DNA. Here, we determine the 2 Å crystal structure of Rhodobact...

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Detalles Bibliográficos
Autores principales: Miyoshi, Tomohiro, Ito, Kosuke, Murakami, Ryo, Uchiumi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919518/
https://www.ncbi.nlm.nih.gov/pubmed/27325485
http://dx.doi.org/10.1038/ncomms11846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919518/
https://www.ncbi.nlm.nih.gov/pubmed/27325485
http://dx.doi.org/10.1038/ncomms11846

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