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Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

Full-length (FL) docking protein-1 (DOK1) is an adapter protein which inhibits growth factor and immune response pathways in normal tissues, but is frequently lost in human cancers. Small DOK1 variants remain in cells of solid tumors and leukemias, albeit, their functions are elusive. To assess the...

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Detalles Bibliográficos
Autores principales: Friedrich, Teresa, Söhn, Michaela, Gutting, Tobias, Janssen, Klaus-Peter, Behrens, Hans-Michael, Röcken, Christoph, Ebert, Matthias P.A., Burgermeister, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919572/
https://www.ncbi.nlm.nih.gov/pubmed/27428427
http://dx.doi.org/10.1016/j.ebiom.2016.05.003