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Gap Junctions Contribute to Ictal/Interictal Genesis in Human Hypothalamic Hamartomas

Human hypothalamic hamartoma (HH) is a rare subcortical lesion associated with treatment-resistant epilepsy. Cellular mechanisms responsible for epileptogenesis are unknown. We hypothesized that neuronal gap junctions contribute to epileptogenesis through synchronous activity within the neuron netwo...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Gao, Ming, Rice, Stephen G., Tsang, Candy, Beggs, John, Turner, Dharshaun, Li, Guohui, Yang, Bo, Xia, Kunkun, Gao, Fenfei, Qiu, Shenfeng, Liu, Qiang, Kerrigan, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919609/
https://www.ncbi.nlm.nih.gov/pubmed/27428422
http://dx.doi.org/10.1016/j.ebiom.2016.04.026