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Evolution of 2009 H1N1 influenza viruses during the pandemic correlates with increased viral pathogenicity and transmissibility in the ferret model

There is increasing evidence that 2009 pandemic H1N1 influenza viruses have evolved after pandemic onset giving rise to severe epidemics in subsequent waves. However, it still remains unclear which viral determinants might have contributed to disease severity after pandemic initiation. Here, we show...

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Detalles Bibliográficos
Autores principales: Otte, Anna, Marriott, Anthony C., Dreier, Carola, Dove, Brian, Mooren, Kyra, Klingen, Thorsten R., Sauter, Martina, Thompson, Katy-Anne, Bennett, Allan, Klingel, Karin, van Riel, Debby, McHardy, Alice C., Carroll, Miles W., Gabriel, Gülsah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919623/
https://www.ncbi.nlm.nih.gov/pubmed/27339001
http://dx.doi.org/10.1038/srep28583