Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice

Macrophages have been recognized as an important inflammatory component in choroidal neovascularization (CNV). However, it is unclear how these cells are activated and polarized, how they affect angiogenesis and what the underlining mechanisms are during CNV. Notch signaling has been implicated in m...

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Detalles Bibliográficos
Autores principales: Dou, Guo-Rui, Li, Na, Chang, Tian-Fang, Zhang, Ping, Gao, Xiang, Yan, Xian-Chun, Liang, Liang, Han, Hua, Wang, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919651/
https://www.ncbi.nlm.nih.gov/pubmed/27339903
http://dx.doi.org/10.1038/srep28617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919651/
https://www.ncbi.nlm.nih.gov/pubmed/27339903
http://dx.doi.org/10.1038/srep28617

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