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LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

Persistence of latent, replication-competent Human Immunodeficiency Virus type 1 (HIV-1) provirus is the main impediment towards a cure for HIV/AIDS (Acquired Immune Deficiency Syndrome). Therefore, different therapeutic strategies to eliminate the viral reservoirs are currently being explored. We h...

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Detalles Bibliográficos
Autores principales: Vranckx, Lenard S., Demeulemeester, Jonas, Saleh, Suha, Boll, Annegret, Vansant, Gerlinde, Schrijvers, Rik, Weydert, Caroline, Battivelli, Emilie, Verdin, Eric, Cereseto, Anna, Christ, Frauke, Gijsbers, Rik, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919729/
https://www.ncbi.nlm.nih.gov/pubmed/27428435
http://dx.doi.org/10.1016/j.ebiom.2016.04.039