Prostacyclin reverses the cigarette smoke-induced decrease in pulmonary Frizzled 9 expression through miR-31

Half of lung cancers are diagnosed in former smokers, leading to a significant treatment burden in this population. Chemoprevention in former smokers using the prostacyclin analogue iloprost reduces endobronchial dysplasia, a premalignant lung lesion. Iloprost requires the presence of the WNT recept...

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Detalles Bibliográficos
Autores principales: Tennis, M. A., New, M. L., McArthur, D. G., Merrick, D. T., Dwyer-Nield, L. D., Keith, R. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919780/
https://www.ncbi.nlm.nih.gov/pubmed/27339092
http://dx.doi.org/10.1038/srep28519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919780/
https://www.ncbi.nlm.nih.gov/pubmed/27339092
http://dx.doi.org/10.1038/srep28519

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