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Vascular-targeted TNFα and IFNγ inhibits orthotopic colorectal tumor growth
BACKGROUND: Tumor necrosis factor alpha (TNFα) and interferon gamma (IFNγ) were originally identified to show potent anti-tumor activity and immunomodulatory capability. Unfortunately, several clinical studies of relevant cancer therapy did not observe significant response in maximum tolerated dose...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919862/ https://www.ncbi.nlm.nih.gov/pubmed/27342639 http://dx.doi.org/10.1186/s12967-016-0944-3 |