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The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment

Background: Hepatocytes metabolize the vast majority of ingested ethanol. This metabolic activity results in hepatic toxicity and impairs the ability of hepatocytes to replicate. Previous work by our group has shown that ethanol metabolism results in a G2/M cell cycle arrest. The intent of these stu...

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Detalles Bibliográficos
Autores principales: Scheer, Marc A., Schneider, Katrina J., Finnigan, Rochelle L., Maloney, Eamon P., Wells, Mark A., Clemens, Dahn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919912/
https://www.ncbi.nlm.nih.gov/pubmed/27043646
http://dx.doi.org/10.3390/biom6020017