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The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment
Background: Hepatocytes metabolize the vast majority of ingested ethanol. This metabolic activity results in hepatic toxicity and impairs the ability of hepatocytes to replicate. Previous work by our group has shown that ethanol metabolism results in a G2/M cell cycle arrest. The intent of these stu...
Autores principales: | Scheer, Marc A., Schneider, Katrina J., Finnigan, Rochelle L., Maloney, Eamon P., Wells, Mark A., Clemens, Dahn L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919912/ https://www.ncbi.nlm.nih.gov/pubmed/27043646 http://dx.doi.org/10.3390/biom6020017 |
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