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Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer’s Disease
Alzheimer’s disease is characterized by redistribution of the tau protein pool from soluble to aggregated states. Aggregation forms proteolytically stable core polymers restricted to the repeat domain, and this binding interaction has prion-like properties. We have compared the binding properties of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919914/ https://www.ncbi.nlm.nih.gov/pubmed/27070645 http://dx.doi.org/10.3390/biom6020019 |