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AurkA controls self-renewal of breast cancer-initiating cells promoting wnt3a stabilization through suppression of miR-128

AurkA overexpression was previously found in breast cancer and associated to its ability in controlling chromosome segregation during mitosis, however whether it may affect breast cancer cells, endorsed with stem properties (BCICs), is still unclear. Surprisingly, a strong correlation between AurkA...

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Detalles Bibliográficos
Autores principales: Eterno, V., Zambelli, A., Villani, L., Tuscano, A., Manera, S., Spitaleri, A., Pavesi, L., Amato, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920028/
https://www.ncbi.nlm.nih.gov/pubmed/27341528
http://dx.doi.org/10.1038/srep28436