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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis

Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of successful brain aging strategies. Here, we used Caenorhabdits elegans to investigate how the expression of proteotoxic triggers, such as polyglu...

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Detalles Bibliográficos
Autores principales: Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920063/
https://www.ncbi.nlm.nih.gov/pubmed/27347427
http://dx.doi.org/10.1038/npjamd.2016.1