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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis
Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of successful brain aging strategies. Here, we used Caenorhabdits elegans to investigate how the expression of proteotoxic triggers, such as polyglu...
Autores principales: | Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920063/ https://www.ncbi.nlm.nih.gov/pubmed/27347427 http://dx.doi.org/10.1038/npjamd.2016.1 |
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