repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data

Motivation: The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are composed of random events—choices of gene templates, base pair deletions and insertions—described by probability...

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Detalles Bibliográficos
Autores principales: Elhanati, Yuval, Marcou, Quentin, Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920122/
https://www.ncbi.nlm.nih.gov/pubmed/27153709
http://dx.doi.org/10.1093/bioinformatics/btw112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920122/
https://www.ncbi.nlm.nih.gov/pubmed/27153709
http://dx.doi.org/10.1093/bioinformatics/btw112

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