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repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Motivation: The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are composed of random events—choices of gene templates, base pair deletions and insertions—described by probability...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920122/ https://www.ncbi.nlm.nih.gov/pubmed/27153709 http://dx.doi.org/10.1093/bioinformatics/btw112 |