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TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice

Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS). In addition to TLRs, CD80 has been shown to be essential for PAMP-mediated al...

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Detalles Bibliográficos
Autores principales: Jain, Nidhi, Khullar, Bhavya, Oswal, Neelam, Banoth, Balaji, Joshi, Prashant, Ravindran, Balachandran, Panda, Subrat, Basak, Soumen, George, Anna, Rath, Satyajit, Bal, Vineeta, Sopory, Shailaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920147/
https://www.ncbi.nlm.nih.gov/pubmed/27125280
http://dx.doi.org/10.1242/dmm.023440