2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration

The correct migration and axon extension of neurons in the developing nervous system is essential for the appropriate wiring and function of neural networks. Here, we report that O-sulfotransferases, a class of enzymes that modify heparan sulfate proteoglycans (HSPGs), are essential to regulate neur...

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Detalles Bibliográficos
Autores principales: Tillo, Miguel, Charoy, Camille, Schwarz, Quenten, Maden, Charlotte H., Davidson, Kathryn, Fantin, Alessandro, Ruhrberg, Christiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920156/
https://www.ncbi.nlm.nih.gov/pubmed/27048738
http://dx.doi.org/10.1242/dev.126854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920156/
https://www.ncbi.nlm.nih.gov/pubmed/27048738
http://dx.doi.org/10.1242/dev.126854

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