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De novo neurogenesis by targeted expression of atoh7 to Müller glia cells

Regenerative responses in the vertebrate CNS depend on quiescent radial glia stem cells, which re-enter the cell cycle and eventually differentiate into neurons. The entry into the cell cycle and the differentiation into neurons are events of opposite nature, and therefore efforts to force quiescent...

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Detalles Bibliográficos
Autores principales: Lust, Katharina, Sinn, Rebecca, Pérez Saturnino, Alicia, Centanin, Lázaro, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920165/
https://www.ncbi.nlm.nih.gov/pubmed/27068106
http://dx.doi.org/10.1242/dev.135905