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In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells

Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells. Recently, peripheral blood mononuclear cells (PBMCs) have attracted considerable attention as a somatic cell source for reprogramming. As a cell...

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Detalles Bibliográficos
Autores principales: Komuta, Yukari, Ishii, Toshiyuki, Kaneda, Makoto, Ueda, Yasuji, Miyamoto, Kiyoko, Toyoda, Masashi, Umezawa, Akihiro, Seko, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920181/
https://www.ncbi.nlm.nih.gov/pubmed/27170256
http://dx.doi.org/10.1242/bio.016477