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Downregulation of leptin inhibits growth and induces apoptosis of lung cancer cells via the Notch and JAK/STAT3 signaling pathways

Previous studies have documented that leptin is involved in the pathogenesis of many human cancer types by regulation of numerous signal transduction pathways. The aim of this study was to investigate the biological roles of leptin and the mechanisms attributed to its action in non-small cell lung c...

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Detalles Bibliográficos
Autores principales: Zheng, Xian-Jie, Yang, Zhong-Xin, Dong, Yan-Jun, Zhang, Guo-Yu, Sun, Ming-Fei, An, Xiao-Kang, Pan, Li-Hong, Zhang, Shuang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920192/
https://www.ncbi.nlm.nih.gov/pubmed/27185268
http://dx.doi.org/10.1242/bio.017798