A novel pH–enzyme-dependent mesalamine colon-specific delivery system

The aim of the present study was to design a new pH–enzyme double-dependent mesalamine colon-specific delivery system. The drug release behaviors in vitro and pharmacokinetics and biodistribution in vivo were further evaluated. The mean particle diameters of mesalamine-coated microparticles were 312...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Ding, Yi-cun, Zhang, Yu, Xu, Xiao-qing, Cao, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920224/
https://www.ncbi.nlm.nih.gov/pubmed/27382255
http://dx.doi.org/10.2147/DDDT.S107283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920224/
https://www.ncbi.nlm.nih.gov/pubmed/27382255
http://dx.doi.org/10.2147/DDDT.S107283

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