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Sumoylation of eIF4A2 affects stress granule formation

Regulation of protein synthesis is crucial for cells to maintain viability and to prevent unscheduled proliferation that could lead to tumorigenesis. Exposure to stress results in stalling of translation, with many translation initiation factors, ribosomal subunits and mRNAs being sequestered into s...

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Detalles Bibliográficos
Autores principales: Jongjitwimol, Jirapas, Baldock, Robert A., Morley, Simon J., Watts, Felicity Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920252/
https://www.ncbi.nlm.nih.gov/pubmed/27160682
http://dx.doi.org/10.1242/jcs.184614