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Sumoylation of eIF4A2 affects stress granule formation
Regulation of protein synthesis is crucial for cells to maintain viability and to prevent unscheduled proliferation that could lead to tumorigenesis. Exposure to stress results in stalling of translation, with many translation initiation factors, ribosomal subunits and mRNAs being sequestered into s...
Autores principales: | Jongjitwimol, Jirapas, Baldock, Robert A., Morley, Simon J., Watts, Felicity Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920252/ https://www.ncbi.nlm.nih.gov/pubmed/27160682 http://dx.doi.org/10.1242/jcs.184614 |
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