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Mutation rates and the evolution of germline structure
Genome sequencing studies of de novo mutations in humans have revealed surprising incongruities in our understanding of human germline mutation. In particular, the mutation rate observed in modern humans is substantially lower than that estimated from calibration against the fossil record, and the p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920338/ https://www.ncbi.nlm.nih.gov/pubmed/27325834 http://dx.doi.org/10.1098/rstb.2015.0137 |