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Natural Polymorphisms Conferring Resistance to HCV Protease and Polymerase Inhibitors in Treatment-Naïve HIV/HCV Co-Infected Patients in China

BACKGROUND: The advent of direct-acting agents (DAAs) has improved treatment of HCV in HIV co-infection, but may be limited by primary drug resistance. This study reports the prevalence of natural polymorphisms conferring resistance to NS3/4A protease inhibitors and NS5B polymerase inhibitors in tre...

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Detalles Bibliográficos
Autores principales: Zhou, Kali, Liang, Zhiwei, Wang, Charles, Hu, Fengyu, Ning, Chuanyi, Lan, Yun, Tang, Xiaoping, Tucker, Joseph D., Cai, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920402/
https://www.ncbi.nlm.nih.gov/pubmed/27341031
http://dx.doi.org/10.1371/journal.pone.0157438